Bìol. Tvarin. 2021; 23 (2): 41–45.
Received 20.05.2021 ▪ Accepted 25.06.2021 ▪ Published online 01.07.2021

Features of the influence of oat extract on the antioxidant activity of goose liver

Yu. V. Nikolaeva1, O. O. Danchenko2

This email address is being protected from spambots. You need JavaScript enabled to view it.

1Bogdan Khmelnitsky Melitopol State Pedagogical University.
20 Hetmanska str., Melitopol, Zaporizhzhya district, 72312, Ukraine

2Dmytro Motornyi Tavria state agrotechnological university,
18 Bohdan Kmelnytsky ave., Melitopol, Zaporizhzhya district, 72312, Ukraine

The use of antioxidants in poultry feeding helps to relieve stress of various etiologies. Natural antioxidants have a number of advantages over synthetic ones. The aim of the study was to determine the effect of Avena sativa oat extract on the peculiarities of the functioning of the antioxidant system of goose liver during the physiological stress of contour and juvenile feather formation (from the 14th to the 56th day). The state of the antioxidant system in liver tissues was determined by the coefficient of antioxidant activity, the content of the final products of lipoperoxidation, the activity of antioxidant enzymes and the content of fat-soluble vitamins. The results of the experiment showed that the goslings of the control group during the formation of contour feathers have a decrease in antioxidant activity of the liver by 2.36 times, and juvenile — 1.90 times compared to the initial value of this indicator. Adding oat extract to the diet of geese during feather formation increases the antioxidant activity of their liver. Under the influence of the extract, the physiological stress associated with the formation of contour feathers (28 days) is significantly reduced by reducing the content of the main substrate of lipoperoxidation of unsaturated fatty acids, despite the decrease in the activity of all antioxidant enzymes. Increasing antioxidant activity in the liver during the formation of juvenile feathers is due to the inclusion of alternative mechanisms of antioxidant protection, implemented by increasing the activity of endogenous antioxidants: superoxide dismutase by 29.6 (P≤0.05), catalase by 34.6% (P≤0.05), glutathioperoxidase by 41.2% (P≤0.01), and the content of vitamin E by 32.7% (P≤0.05) and β-carotene by 30.9% (P≤0,05). Under the influence of the extract there is not only a significant increase in the weight of geese at the end of the experiment, but also an improvement in their pterylographic performance. Therefore, in the future, it would be advisable to conduct similar studies on wild bird species in kennels, as the process of feather formation is of fundamental importance for these birds.

Key words: antioxidant activity, lipoperoxidation products, enzymes, vitamins, liver, physiological stress, feather formation, pterylographic indicators

  1. Abreu IA, Cabelli DE. Superoxide dismutases-a review of the metal-associated mechanistic variations. Biochim. Biophys. Acta. 2010; 1804 (2): 263–274. DOI: 10.1016/j.bbapap.2009.11.005.
  2. Antonini E, Diamantini G, Ninfali P. The effect of mechanical processing on avenanthramide and phenol levels in two organically grown Italian oat cultivars. J. Food Sci. Technol. 2017; 54: 2279–2287. DOI: 10.1007/s13197-017-2665-x.
  3. Bratyshko NI, Gorobets AI, Prytulenko OV. Recommendations for rationing of poultry feeding. Ed. by YO Ryabokonya. Borku, Research Institute of Poultry, 2005: 104 p. (in Ukrainian)
  4. Damiano F, Giannotti L, Gnoni GV, Siculella L, Gnoni A. Quercetin inhibition of SREBPs and ChREBP expression results in reduced cholesterol and fatty acid synthesis in C6 glioma cells. Int. J. Biochem. Cell Biol. 2019; 117: 105618. DOI: 10.1016/j.biocel.2019.105618.
  5. Danchenko OO. The level of consistency of pro-antioxidant balance of goose liver as a criterion for the damaging effects of technological factors. Sci. Messenger Scientific Messenger LNU Vet. Med. Biotechnol. 2009; 11, 3 (42): 26–34. (in Ukrainian)
  6. Danchenko OO, Kalitka VV, Kolesnik DM. Ontogenetic features of changes in fatty acid composition of goose liver lipids as the main substrate of peroxidation. Ukr. Biochem. J. 2003; 75 (3): 124–129. (in Ukrainian)
  7. Danchenko OO, Pashchenko JP, Danchenko NM, Zdorovtseva LM. Mechanisms of support prooxidant-antioxidant balance in the liver tissues of geese in hypo- and hyperoxia. Ukr. Biochem. J. 2012; 84 (6): 109–114. Available at: http://ua.ukrbiochemjournal.org/2016/05/mehanizmy-pidtrymky-prooksydantno-antyoksydantnoji-rivnovahy-v-tkanynah-pechinky-husej-v-umovah-hipo-i-hiperoksiji.html (in Ukrainian)
  8. Danchenko O, Zdorovtseva L, Vishchur O, Koshelev O, Halko T, Danchenko M, Nikolayeva Yu, Mayboroda D. Extract of oats as a modulator of fatty acid composition of geese tissues in the conditions of physiological stress. Biologija. 2020; 66 (1): 27–34. DOI: 10.6001/biologija.v66i1.4188.
  9. Fedorovich EI, Zaplatynsky VS. Current situation and perspectives of geese farming in Ukraine. Sci. Messenger Scientific Messenger LNU Vet. Med. Biotechnol. Ser. Vet. Med. 2015; 17 (3): 322–329. Available at: https://nvlvet.com.ua/index.php/journal/article/view/570 (in Ukrainian)
  10. Ionov IA, Shapovalov SO, Rudenko EV, Dolgaya MN, Akhtyrsky AV, Zozulya YA, Komisova TE, Kostyuk IA. Criteria and methods for controlling metabolism in the body of animals and birds. Kharkiv, Institute of Animal Husbandry NAAS, 2011: 378 p. (in Russian)
  11. Jágr M, Dvořáček V, Čepková PH, Doležalová J. Comprehensive analysis of oat avenanthramides using hybrid quadrupole-Orbitrap mass spectrometry: Possible detection of new compounds. Rapid Commun. Mass. Spectrom. 2020; 34 (10): e8718. DOI: 10.1002/rcm.8718.
  12. Landau S, Everitt BS. A handbook of statistical analyses using SPSS. Chapman and Hall/CRC. 2003, 366 p. ISBN 9780203009765. DOI: 10.1201/9780203009765.
  13. Ltaif M, Gargouri M, Magné C, El Feki A, Soussi A. Protective effects of Avena sativa against oxidative stress-induced kidney damage resulting from an estrogen deficiency in ovariectomized Swiss mice model. J. Food Biochem. 2020: e13205. DOI: 10.1111/jfbc.13205.
  14. Meydani M. Potential health benefits of avenanthramides of oats. Nutr. Rev. 2009; 67 (12): 731–735. DOI: 10.1111/j.1753-4887.2009.00256.x.
  15. Montilla-Bascón G, Broeckling CD, Hoekenga OA, Prats E, Sorrells M, Isidro-Sánchez J. Chromatographic methods to evaluate nutritional quality in oat. Methods Mol. Biol. 2017; 1536: 115–125. DOI: 10.1007/978-1-4939-6682-0_8.
  16. Nie L, Wise ML, Peterson DM, Meydani M. Avenanthramide a polyphenol from oats, inhibits vascular smooth muscle cell proliferation and enhances nitric oxide production. Atherosclerosis. 2006; 186 (2): 260–266. DOI: 10.1016/j.atherosclerosis.2005.07.027.
  17. Rostova NS. Correlations: structure and variability. Saint Petersburg, Publishing house of SPbSU, 2002: 307 p. (in Russian)
  18. Singh R, De S, Belkheir A. Avena sativa (oat), a potential neutraceutical and therapeutic agent: an overview. Crit. Rev. Food Sci. Nutr. 2013; 53 (2): 126–144. DOI: 10.1080/10408398.2010.526725.
  19. Tian WX. Inhibition of fatty acid synthase by polyphenols. Curr. Med. Chem. 2006; 13 (8): 967–977. DOI: 10.2174/092986706776361012.
  20. Vauzour D, Tejera N, O’Neill C, Booz V, Jude B, Wolf IMA, Rigby N, Silvan JM, Curtis PJ, Cassidy A, de Pascual-Teresa S, Rimbach G, Minihane AM. Anthocyanins do not influence long-chain n-3 fatty acid status: studies in cells, rodents and humans. J. Nutr. Biochem. 2015; 26 (3): 211–218. DOI: 10.1016/j.jnutbio.2014.09.005.
  21. Viskupičová J, Ondrejovič M, Šturdík E. Bioavailability and metabolism of flavonoids. J. Food Nutr. Res. 2008; 47 (4): 151–162.
  22. Zdorovtseva LM, Khromishev VO, Danchenko OO. Fatty acid composition of lipids of the brain and heart of geese in hypo- and hyperoxia. Biol. Bull. Mеlitopol State Ped. Univ. 2012; 2 (3): 9–18. DOI: 10.7905/bbmspu.v0i3(6).543. (in Ukrainian)
  23. Zhang JS, Lei JP, Wei GQ, Chen H, Ma CY, Jiang HZ. Natural fatty acid synthase inhibitors as potent therapeutic agents for cancers: a review. Pharm Biol. 2016; 54 (9): 1919–1925. DOI: 10.3109/13880209.2015.1113995.

gslogo

ICLOGO

cr

nbuv

ouci0

WorldCat Logo

oa

Search