GLUCOCOTICOSTEROID ACTIVITY OF THE ADRENAL GLANDS OF COWS DURING PREGNANCY AND FOR ORTHOPEDIC, OBSTETRIC AND GYNECOLOGICAL PATHOLOGIES

Bìol. Tvarin, 2016, vol. 18, no. 1, pp. 9–16

https://doi.org/10.15407/animbiol18.01.009

GLUCOCOTICOSTEROID ACTIVITY OF THE ADRENAL GLANDS OF COWS DURING PREGNANCY AND FOR ORTHOPEDIC, OBSTETRIC AND GYNECOLOGICAL PATHOLOGIES

S. Vlasenko

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Bila Tserkva National Agrarian University,
8/1 Soborna sq., Bila Tserkva 09111, Ukraine

Endocrine research was performed by ELISA. Cortisol was determined in the blood serum of cows during pregnancy, 3–5 day after childbirth, at acute postpartum metritis, ovarian hypofunction, persistence of corpus luteum, luteal cysts and oophoritis. Thus, the control animals had healthy limbs, and the research ones had the pulp and interdigital vault skin ulcers, cellulitis edges, purulent pododermatitis.

It has been established that cortisol dynamics in cows during pregnancy and after childbirth underwent significant alteration and was characterized by alternating periods of increase and decrease of hormone. In second and third months it was 1.41±0.45 and 1.22±0.25 mcg/dl. During the fourth month we observed its double increase, and the on fifth month it reached a maximum value — 3.02±0.44 mcg/dl. The sixth month of pregnancy was characterized by a sharp decrease in the concentration by 46.4 % — to 1.62±0.17 mcg/dl, and in the next two months there were minor fluctuations. Preparation for childbirth ran with the level of cortisol lowered 1.7 times, however, during the first 3–5 days of puerperal period the increase to 1.63±0.45 mcg/dl was noted. The development of acute postpartum metritis predetermined increase in cortisol concentrations 2.3 times, persistent corpus luteum — 7.2 times, oophoritis — 6 times.

For purulent necrotic processes in the distal extremities in all patients cows, regardless of reproductive status, hormone concentration was higher by 20,4–67,7 % compared to control animals. In addition, the difference between the rates was negligible during pregnancy that graded them within 2.63±0.31–3.99±0.46 mcg/dl. In cases of associated orthopedic pathology in cows after birth and inflammation of the uterine the contents of cortisol in serum underwent a likely increase 2.5 times compared to clinically healthy animals and reached 4.12±1.08 mcg/dl.

Keywords: COW, CORTISOL, IMMUNOFERMENTAL ANALYSIS, PREGNANCY, POSTNATAL PERIOD, ORTHOPEDIC PATHOLOGY, METRITIS, HYPOFUNCTION OF OVARIES, HYPOTROPHIC OF OVARIES, PERSISTENS CORPUS LUTEUM, LUTEAL CYST, OOPHORITIS

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