Bìol. Tvarin, 2018, volume 20, issue 2, pp. 43–50


R. V. Hunchak, H. M. Sedilo

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Institute of Agriculture of the Carpathian Region National Academy of Agrarian Sciences,
5 Hrushevskoho str., Obroshyno village, Pustomyty district, Lviv region, 81115, Ukraine

The article presents the results of study on the iodine aqua citrate impact on metabolism and productive qualities in piglets from ablactation to intensive feeding (2970 days). Complete feed with gramineous group of concentrated feed of domestic production (Polissia area of Volyn) was used. Iodine content in the form of potassium iodide in premix to prestarter and starter compound feed of control group was 0.80 and 1.50 mg/kg respectively. We included iodine aqua citrate (made using nanotechnologies of Avatar Scientific and Production Company, LLC) into the diet of 1st and 2nd experimental group animals at the rate of 50 % and 25 % from the level of bioelement in premixes in KJ form.

It has been established that iodine with its extensive bioavailability as aqua citrate has a stimulating impact on metabolic processes in piglets. In particular, replacement of the recommended dose of inorganic iodine in premix with its citrate nano formulation promotes body weight increase in animals of the experimental group by 5.5 % (P<0.025) and 9.6 % as compared to analogs of the experimental group. Under such conditions hemoglobin, RBC and WBC levels in blood serum were in inverse proportion to levels of iodine consumed in its citrate form, which attests to enhanced levels of body defenses. At the same time, enhanced concentration of protein bound iodine and thyroid hormones have been detected in blood of experimental group piglets, which was stipulated by optimization of thyroid hormonegenesis. Experimental group piglets as compared to control had their levels of total blood protein unchanged yet with characteristic increase of globulin protein fraction levels by 4.1 and 5.9 %, respectively (P<0,05) and urea concentration as well as decrease of excess nitrogen and glucose levels.


  1. Alyoshin B. V. Hypothalamus and thyroid. Moscow, Medicine, 1983, 184 p. (in Russian)
  2. Antonyak G. L., Vlizlo V. V. Biochemical and geochemical role of iodine. A monograph. Lviv, 2013, 390 p. (in Ukrainian)
  3. Borisevich V. B., Kaplunenko V. G., Kosinov N. V. Nanomaterials in biology. Fundamentals of nanoveterinary. Kyiv, WA “Avicenna”, 2010, 416 p. (in Ukrainian)
  4. Chumachenko V. V. Biochemical and immunological basis of the system of prevention of stress in pigs. Dr. veterinary sci. diss., Kyiv, 2007, 440 p. (in Ukrainian)
  5. EU (European Community), 2005:1459/2005/EC Commission Regulation (EC). No feed additives belonging to the group of trace elements. Official Journal of the European Union, L, 2005, pp. 8–10.
  6. He M., Hollwich W., Rambeck W. Supplementation of algae to the diet of pigs: a new possibility to improve the iodine content in the meat. Anim. Physiol. Anim. Nutr. (Berl)., 2002, vol. 86(3–4), pp. 97–104. https://doi.org/10.1046/j.1439-0396.2002.00363.x
  7. Herzig I., Pisarikova B., Diblikova I., Suchy P. Iodine concentration in porcine blood, urine, and tissues after a single dose of iodised oil. Veterinarni Medicina, 2001, no. 46, pp. 153–159. https://doi.org/10.17221/7875-VETMED
  8. Hunchak R., Sedilo G., Vovk S. Iodine content in soils and grains of cereals in Polissia area of Volyn region. XXII Sesja Sekcji Młodej Kadry Naukowej Polskiego Towarzystwa Technologów Żywności — 5th International Session of Young Scientific Staff, May 18–19th, Szczecin (Poland), 2017, pp. 121–125.
  9. Kalnitskiy B. D. Mineral substances in feeding of animals. Leningrad, Agropromizdat. Leningrad deparment, 1985, 207 p. (in Ukrainian)
  10. Lyashenko V. M., Vintonyak V. M., Slipinyuk O. V. Using premixes with increased contents of cobalt, copper, and iodine for intensive fattening of pigs. Bulletin of the Center for Science Provision of Agribusiness in the Kharkiv region, 2015, no. 18, pp. 202–206. (in Ukrainian)
  11. Khomyn M. M., Fedoruk R. S., Khrabko M. I. Influence of iodine nanoakvahidrate on biochemical parameters of milk and milk productivity of cows in the first month of lactation. Scientific Messenger of Lviv National University of Veterinary Medicine and Biotechnologies, 2015, vol. 17, no. 1 (61), pp. 243–247. (in Ukrainian)
  12. Mamtsev A., Kozlov V., Grigorev V., Maksyutov R. Synthesis of iodine-containing nano-dispersed composites. Samara State Agricultural Academy, 2016, no.4, pp. 79–84. (in Russian)
  13. Panchenko L. F., Maev I. V., Gurevich K. G. Clinical chemistry of trace elements. Moscow, 2004, 368 p. (in Russian)
  14. Preedy V. R., Burrow G. N., Watson R. R. Comprehensive Handbook of Jodine: Nutritional, Biochemical, Pathological and Therapenic Aspects. Acal. Press, 2009, pp. 13–12.
  15. Romanenko T. G., Chayka O. I. Features of thyroid function in pregnant women against iodine deficiency. International journal of endocrinology, 2014, no. 4(60), pp. 89–94. (in Russian)
  16. Sedilo G. M. A role of mineral substances in the processes of wool formation. Lviv, Afisha, 2002, 184 p. (in Ukrainian)
  17. Sedilo H. M., Hunchak R. V., Vovk S. O. Contents of iodine and thyroid hormones in sows blood for a different level of iodine citrate in their diets. Bulletin of Sumy National Agrarian University, 2017, vol. 7 (33), pp. 206–2011. (in Ukrainian)
  18. Shesterynska V. V., Trokoz V. O., Karpovskiy V. I., Maksin V. I., Kryvoruchko D. I. Dynamics of glucose in the blood of pigs of different types nervous systems with addition to the diet “jodis-concentrate”. The Animal Biology, 2012, vol. 14, no. 1–2, pp. 295–299. (in Ukrainian)
  19. Silva J. E. Thyroid Hormone Control of Thermogenesis and Energy Balance. Thyroid, 1995, no. 5 (6), pp. 481–492.
  20. Slyusarenko A. E., Evstafeva E. V. Immunotropic action of iron, cobalt, manganese, nickel, calcium and lead in the conditions of base-line contamination of municipal environment. Pathology, 2011, vol. 8, no. 2, pp. 124–126 (in Russian)
  21. Sologub L. I. , Antonyak G. L., Antonyak T. O. Iodine in the organism of animals and humans (Biochemical aspects). The Animal Biology, 2005, vol. 7, no. 1–2, pp. 31–50. (in Ukrainian)
  22. Spiridonov A. A., Murashov E. V., Kislova O. F. Iodine supplementation of livestock products. Norms and technologies. Saint Petersburg, SPS-Print, 2011, pp. 21–38. (in Russian)
  23. Vezhentsev A., Kravtsiv R., Pivtorak Ya. Normalized feeding of pigs. Lviv, 2004, pp. 7–10. (in Ukrainian)
  24. Vlizlo V. V., Fedoruk R. S., Ratych I. B. Laboratory methods of investigation in biology, stock-breeding and veterinary. A reference book, ed. by V. V. Vlizlo. Lviv, Spolom, 2012, 764 p. (in Ukrainian)
  25. Vorobev D. V. Effect of selenium, iodine and copper preparations On the processes of metabolism of growing pigs at hypoelementoses. Agrarian Bulletin of the Urals, 2011, no. 12, pp. 116–120. (in Russian)

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