Bìol. Tvarin, 2019, volume 21, issue 3, pp. 56–60


I. Matiukha, N. Broda, D. Mudrak, K. Smolyaninov

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Institute of Animal Biology NAAS,
38 V. Stus str., Lviv 79034, Ukraine

Environmental contamination by xenobiotics has a crucial negative impact on productive animals’ health by reducing immune reactivity and causing metabolic disorders. One of the ecologically dangerous objects in Ukraine is the Lviv-Volyn coal basin. Thus the aim of our study was to investigate the influence of subcutaneous injections of vitamin drug in liposomal form on the performance, antioxidant and immune status of heifers and their calves under technogenic load. Investigation and the explanation of the influence of experimental drug “Pregnavitan” on the intensity of metabolism of vital important vitamins A and E, intensity of antioxidant defense in cows and their calves was the main aim of our work. The research has showed the tendency to growing the number of leucocytes, and the decrease of total protein content and current indexes of cell and humoral links of immune defense with the increase of gestation time in the blood of cow’s established. This suggests the development of physiological immunosuppresion in pregnant animals. Intramuscular injection in the last month of pregnancy of vitamins A, D3, E, lecithin, methionine and cobalt acetate in the form of liposomal emulsion improves natural resistance of cows and received of them calves. The parenteral injection of liposomal drug “Pregnavitan” to pregnant cows and newborn calves enhances the natural resistance of their organisms and recovery red-ox balance in their body. In these circumstances, the drug we have developed for the needs of animals: essential vitamins, trace elements and biologically active substances. In general, that composition had positive effects on metabolic processes in animals.


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