The activity of immunological indicators in chickens with the complex use of a symbiotic drug “Biomagn” and a disinfectant “Diolide”
O. Chechet1, O. Vishchur2, V. Kovalenko1, B. Kurtyak3, K. Smolyaninov2, A. Voltornistyi2
1State Scientific and Research Institute of Laboratory Diagnostics and Veterinary and Sanitary Expertise, Kyiv, Ukraine
2Institute of Аnimal Biology of National Academy of Agrarian Sciences of Ukraine, Lviv, Ukraine
3Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv, Ukraine
The goal of the research was to determine the effect of the complex use of symbiotic and disinfectant on immunological indicators in broiler chickens. The research was carried out on ROSS-308 cross broiler chickens. Chickens 1-41 days old (2 groups of 100 chickens) were kept in standard production premises with free access to feed and water, observing the technological parameters of cultivation. The chickens of the research group, in addition to the standard diet, were fed the synbiotic "Biomagn" (0.5 kg/t compound feed) according to the scheme and throughout the experiment they drank the drug "Diolaid" with water (1 mg/l). Blood for immunological studies was collected on 10-27-34-41 days. The study was conducted without violating the guidelines of the EU Directive 2010/63/EU on the protection of animals used for scientific purposes. Complex application of the proposed synbiotic and disinfectant to chickens contributed to an increase in the level of immunological reactivity, as indicated by higher (Р<0.05–0.01) bactericidal and lysozyme activity of blood serum and phagocytic activity of blood pseudoeosinophils of chickens compared to the control, an optimizing effect on the level of circulating immune complexes. So, the results of the research indicate the additive effect of the synbiotic drug "Biomagn" and the disinfectant "Diolide" on the functioning of the mechanisms of natural protection of broiler chickens during their growing period. This effect is due to the complex normalizing effect of the applied agents.
Key words: broiler chickens, symbiotic, chlorine dioxide, bactericidal, lysozyme and phagocytic activity
