Bìol. Tvarin, 2015, volume 17, issue 2, pp. 179–187
VITAMIN D STATUS OF CALVES AT THE FIRST MONTH OF LIFE AFTERDIFFERENTROUTES OF CHOLECALCIFEROLINPUT TO COWS
L. L.Yuskiv, V. V.Vlizlo
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Institute of animal biology NAAS,
38 V. Stus str., Lviv 79034, Ukraine
Vitamin D-status of early postnatal calves obtained from high-performance cows were treated with cholecalciferol orally or intramuscularly in winter-stall period was investigated.Vitamin D was added to the diet in daily dose of 30 IU per 1 kg of body weight for a month starting 7–10 days before the predicted date of calving, and then in 5–7 day after calving. Intramuscularly vitamin D was administered: the first time — at 7–10 days before the predicted date of calving and three more times starting from 5–7th day after calving every 7 days at a dose of 210 IU per 1 kg of body weight for each input.For studies in calves for took blood 5–7- and 28–30-th day after birth. In the blood examined the contents of the 25-hydroxyvitamin D, total calcium and its fractions, inorganic phosphorus, magnesium and alkaline phosphatase activity.
It was established that calves derived from cows that in the last days of gestation and after calving were treated with cholecalciferol orally or intramuscularly had higher blood levels of 25-OHD3, total calcium, bounded with protein calcium and ultrafiltrated calcium, inorganic phosphorus, magnesium and lower activity of alkaline phosphatase compared to calves from cows of the control group.
Blood serum of calves born by cow sthat were intramuscular injected with vitamin D3 characterized by significantly higher content of 25-OH D3, calcium and inorganic phosphorus at 5–7th and 28–30th day after birth, compared to calves of control group. Supplementation of cow diet with cholecalciferol showed the effectt on these calf blood parameters onlyon 28–30thday after birth.
Thus, the introduction of cholecalciferol cows in late pregnancy and early lactation is essential to ensure their calves this vitamin in the early postnatal period.
Keywords: COWS, CALVES, VITAMIN D, METABOLISM, BLOOD, 25-HYDROXYCHOLECALCIFEROL, CALCIUM, PHOSPHORUS, MAGNESIUM, ALKALINE PHOSPHATASE
- Levchenko V. I., Vlizlo V. V., Kondrahin I. P. The clinical diagnosis of internal diseases. Bila Tserkva, 2004, 608 p. (in Ukrainian)
- Levchenko V. I., Tihonjuk L. A., Apuhovska L. I. Diagnosis of early forms of D-hypovitaminosis in calves over the content of phosphorus and 2.3 dyfosfohlitseratu in erythrocytes. Bulletin of agrarian science, 1981, no. 9, pp. 73–76. (in Ukrainian)
- Kurtjak B. M., Janovich V. G. Fat-soluble vitamins in veterinary medicine and animal husbandry. Lviv, Triada Pljus, 2004, 426 p. (in Ukrainian)
- Maslova T. V., Egorova G. G. Etiological factors of development of D defytsyt status of calves. Progress of modern natural science, 2005, no. 10, p.68. (in Russian)
- Horst R. L., Reinhardt A. Vitamin D metabolism in ruminants and its relevance to the periparturient cow. J. Dairy Sci., 1983, vol. 66, pp. 661–678. https://doi.org/10.3168/jds.S0022-0302(83)81844-X
- Goff J. P., Horst R. L., Littledike E. T. Effect of maternal vitamin D status at parturition on the vitamin D status of the neonatal calf. J. Nutr., 1982, 112, pp. 1387–1393. https://doi.org/10.1093/jn/112.7.1387
- Barlet J. P., Argemi B., Davicco M., Lefaivre J. Plasma concentrations of 25-hydroxyvitamin D in pregnant and lactating ewes and foetal and newborn lambs. J. Endocrinol., 1978, 79, pp.149–150. https://doi.org/10.1677/joe.0.0790149
- Van Saun R. J. Vitamin D–responsive rickets in neonatal lambs. Can Vet J., 2004, vol. 45, pp. 841–844.
- Reinhardt T. A., Horst R. L., Goff J. P. Calcium, phosphorous, and magnesium homeostasis in ruminants. Vet. Clin. North Am. Food Anim. Pract., 1988, 4, pp. 331–350. https://doi.org/10.1016/S0749-0720(15)31052-5
- Lukyanova E. M., Antipkin Yu. G., Omelchenko L. I., Apuhovskaya L. I. Vitamin D and its role in the Provision of health of children and pregnant women. Kyiv, Expert B, 2005, 230 p. (in Ukrainian)
- Dittmer K. E., Thompson K. G. Vitamin D Metabolism and Rickets in Domestic Animals. A Review. Vet. Pathol., 2011, vol. 48, pp. 389-407. https://doi.org/10.1177/0300985810375240
- Hollis B. W., Lambert P. W., Horst R. L. Factors affecting the antirachitic content of native milk. In: Holick M. F., Ray T. K., Anaste C. S. (eds.). Perinatal calcium and phosphorus metabolism. Elsevier Sci. Publ., B. V., 1983, p. 157.
- De Luca H. F. The vitamin D system in the regulation of calcium and phosphorus metabolism. Nutr. Rev., 1979, 37, pp. 161–193. https://doi.org/10.1111/j.1753-4887.1979.tb06660.x
- Horst R. L., Goff J. P., Reinhardt T. A. Calcium and vitamin D metabolism in the dairy cow. J. Dairy Sci., 1994, 77, pp. 1936–1951. https://doi.org/10.3168/jds.S0022-0302(94)77140-X
- Norman A. W. From vitamin D to hormone D: Fundamentals of the vitamin D endocrine system essential for good health. J. Clin. Nutr., 2008, 88, pp. 491–499. https://doi.org/10.1093/ajcn/88.2.491S
- Goff J. P., Horst L., Littledike E. T. Effect of sow vitamin D status at parturition on the vitamin D status of the neonatal piglets. J. Nutr., 1984, pp. 114–163. https://doi.org/10.1093/jn/114.1.163
- Vlizlo V. V., Fedoruk R. S., Ratych I. B. Laboratory methods of research in biology, veterinary medicine. A guide. Lviv, Spolom, 2012, 764 p. (in Ukrainian)
- Vagner V. K., Putilin V. M., Harabuga G. G. Questions of medical chemistry, 1981, 27, no. 6, pp. 752–754. (in Russian)
- Yuskiv L. L., Vlizlo V. V. Vitamin D Provision in High-Yield Dairy Cows During Winter Housing Period. Agricultural Science and Practice, 2014, vol. 1 (1), pp. 42-46. https://doi.org/10.15407/agrisp1.01.042
- Gascon-Barre M., Plourdo , Haddad P., Martial J. Fetal and neonatal uptake and microsomal C-25 hydroxylation of vitamin D by the rat liver. In: Norman A. W., Schaefer K., Grigolt H.-G., Herra D. V., ed. de Gruyter. Vitamin D. Chemical, biochemical and clinical update. Berlin, 1985, p. 654.
- Durand, D., G. D. Braithwaite, J.-P. Baler. The effect of la-hydroxycholecalciferol on the placental transfer of calcium and phosphate in sheep. Br. J. Nutr., 1983, 49, pp. 475–483. https://doi.org/10.1079/BJN19830056