LIPID METABOLISM IN THE LYMPHOCYTES OF WEANED PIGLETS AFTER ADMINISTRATION OF LIPOSOMAL DRUG «VITARMIN»

Bìol. Tvarin, 2016, vol. 18, no. 1, pp. 105–110

https://doi.org/10.15407/animbiol18.01.105

LIPID METABOLISM IN THE LYMPHOCYTES OF WEANED PIGLETS AFTER ADMINISTRATION OF LIPOSOMAL DRUG «VITARMIN»

N. Z. Ohorodnyk¹, O. I. Vischur¹, K. B. Smolyaninov¹, О. V. Holubets², R. A. Holubets²

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¹Institute of Animal Biology NAAS,
38 V. Stus str., Lviv 79034, Ukraine

²SE «Ukrmetrteststandard»,
4 Metrological str., Kyiv 03143, Ukraine

The influence of the liposomal drug «Vitarmin» on composition of separated classes of lipids and fatty acid profile the lymphocytes of piglets after weaning are presented in the article. The value of certain classes of lipids in the lymphocytes of blood of piglets was determined by thin layer chromatography and fatty acid composition of lipids by capillary gas-liquid chromatography.

On the 10^th day of the weaning piglets from sows, it was observed a significant increase of the content of phospholipids, reducing the content of non-esterified fatty acids and the increase of saturated fatty acids content accompanied with the decline of unsaturated fatty acids. The parenteral administration to the piglets a liposomal drug that contains vitamins A, D₃, E, L-arginine, zinc, selenium, cobalt and magnesium two days before weaning causes the increase of phospholipids content in blood lymphocytes of at the 5^thday after weaning. Reduction of saturated fatty acids and increase of unsaturated fatty acids occurred mostly at the expense of long-chain polyunsaturated fatty acids. The weaning of piglets leads to changes of lipid metabolism in the organism, as evidenced by changes in fatty acid composition of lipids in piglets blood lymphocytes. However, application of complex liposomal drug causes adjusting influence on the content of separate classes of lipids and fatty acid profile of lymphocytes of blood of piglets after weaning them from sows.

Keywords: PIGLETS, WEANING, LIPOSOMAL DRUG, CLASSES OF LIPIDS, FATTY ACID COMPOSITION OF LYMPHOCYTES

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