CHANGES IN THE CONCENTRATION OF FOLLICLE STIMULATING HORMONE AND ESTRADIOL IN DOMESTIC CATS DURING ESTRUS CYCLE AND IN APPLYING OF SYNTHETIC ANALOGUE OF PROGESTERONE
I.V.Shcherbakova
This email address is being protected from spambots. You need JavaScript enabled to view it.
Odessa state agrarian university, Panteleimonivska str., 13, Odessa, 65012, Ukraine1
The article presents data on changes in the concentration of follicle-stimulating hormone in the blood of domestic cats during the estrous cycle and the relationship with the concentration of estradiol in serum depending on ovulation. Cats, which induced ovulation follicle stimulating hormone concentration gradually increases during estrus reaching the maximum value to the fourth day and 2.7 ng/ml, and then gradually decreases to the 10th day of the cycle reaching basal levels. The concentration of estradiol also increased to 42.3 pg/ml fifth day of the cycle, and then rapidly decreases and reaches to the 10th day of the basal value. Cats in which ovulation was induced levels of follicle stimulating hormone was increased by two peaks on the 4th and 10th day of the experiment — 2.6 and 1.8 ng/ml, respectively. This increase coincides with peaks of estradiol concentration in the serum in the same group. The animals which has normal estrous cycle the estradiol levels in serum increased to maximum values — 46.5–47.0 pg/ml to the eighth day of the first manifestations of estrus, coinciding with increasing concentrations of follicle stimulating hormone. Animals treated with megestrol acetate did not show signs of estrus phase transition to, and the low levels observed concentration as follicle stimulating hormone and estradiol. Restoration of the estrus cycle in cats receiving megestrol acetate experienced an average of 10–14 days. Action proliheston was faster and much longer — up to 6 months, due to its deposition in subcutaneous adipose and gradual release over a long period.
Keywords: FOLLICLE-STIMULATING HORMONE, ESTRADIOL, MEGESTROL ACETATE, PROLIHESTON, SYNTHETIC ANALOGUE OF PROGESTERONE, ESTROUS CYCLE, DOMESTIC CATS
