SUS SCROFA SPECIES PARTICULARLY CYTOGENETIC VARIABILITY
S. O. Kostenko1, M. V. Dragulyan2, P. P. Dzhus3
1National University of Life and Environmental Sciences of Ukraine, Kyiv, str. Heroyv Oborony, 12-B, korp.7-A, 03041, Ukraine, This email address is being protected from spambots. You need JavaScript enabled to view it.
2Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv-143, st. Academician Zabolotny 150, 03680 Ukraine, This email address is being protected from spambots. You need JavaScript enabled to view it.
3Institute of Animal Breeding and Genetics NAAS of Ukraine, Kiev region., Boryspil district, s.Chubynske str. Pogrebnyak, 1, 08321, This email address is being protected from spambots. You need JavaScript enabled to view it.
Monіtoring of pig home karyotypic variability continues detect constitutive cytogenetic damage carriers, most of whom are reciprocal translocations. Analyzed the variability of different chromosomes in terms of their length, contents of genes and QTL and participation in cytogenetic damage. Analysis of Sus scrofa population karyotypic variability, which are reproduced in different radioecological conditions, indicates that the cytogenetic parameters of pigs somatic mutagenesis ranges are: the frequency of cells with micronuclei — from 1,3±0,3 to 7,13±0,82 ‰, binucleate — 0,72±0,27 to 5,2±0,3 ‰, mitotic index — from 1,5±0,53 to 10,4±0,4 ‰. The frequency of metaphases with aneuploidy — from 4,50±0,98 to 18,55±3,39 %, asynchronous splitting chromatid centromere regions — from 1,34±0,02 to 6,23±0,05 %, with polyploidy — from 0,3±0,21 to 1,73±0,63 %, with chromosomal aberrations — from 0 to 5,69±0,12 %. Under the influence of low-dose ionizing radiation, there is increased frequency of cells with micronuclei, aneuploidy metaphases, asynchronous cleavage of centromeric regions of chromosomes, dicentric and ring chromosomes.
Key words: CYTOGENETIC MARKERS, THE PIG HOME, ANEUPLOIDY, POLYPLOIDY, MICRONUCLEI, CHROMOSOMAL ABERRATIONS, IONIZING IRRADIATION, SUS SCROFA
