The Animal Biology

INFLUENCE OF DIFFERENT NICKEL CITRATE DOSES ON IMMUNOBIOLOGICAL PARAMETERS AND ANTIOXIDANT PROTECTION SYSTEM OF COWS

O. I. Koleshchuk, I. I. Kovalchuk, M. M. Tsap, M. I. Khrabko

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Institute of Animal Biology NAAS,
38 V. Stusa str., Lviv 79034, Ukraine

The article presents experimental data on the influence of nickel citrate obtained using nanotechnology on immunobiological parameters and antioxidant protection in the body of cows. It has been established that inclusion of nickel citrate in the amount of 0.1 mg/kg s.p. feed (II group) and 0.3 mg/kg s.p. feed (group III) in the diet of cows on the 9^th month of calving and in the first two months after calving positively influenced the functioning of the antioxidant system and the immunobiological parameters of the organism of animals with certain differences. During the first month of feeding in blood of animals of the II group, an increase in the activity of catalase was observed at 11.18 % and SOD at 28 %. In the blood of animals of the III group, there was a slight increase in the activity of catalase by 4.9 % and an increase in the activity of SOD by 18.37 %. During the 2^nd month of feeding, there was an increase in the activity of glutathione peroxidase in the blood of animals of both groups by 10.38 % and 9.91 %, respectively, as well as increase of activity of SOD at 25.25 % in the blood of animals of ІІІ group. Nutrition of cats with Ni citrate for 2 months after calving resulted in a probable decrease in the HPL content: in the blood of cows of the II group by 4.2 %, and in cows of III group by 2.4 %. There was also a tendency towards a decrease in the content of TBK-active products in the blood, which is a terminal metabolite of LPO. Feeding to cows of 0.1 mg/kg nickel citrate (II group) contributed to a probable decrease in the content of circulating immune complexes in their blood serum by 19.2 %, and in ІІ group which was fed 0.3 mg/kg s. feeding stuffs — by 18.9 %.

Keywords: CEREALS, NICKEL CITRUS, ANTIOXIDANT SYSTEM, CATALYSIS, GLUTATHYONPROXIDASE, SUPERROXIDDYSMUTASIS, LIPID HYDROPERTICISM, IMMUNOBIOLOGICAL PARAMETERS

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