Main directions of research and achievements of the Laboratory of ecological physiology and product quality in 2000–2020

I. I. Kovalchuk, R. S. Fedoruk, M. M. Tsap

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The article presents the main directions of research and the most significant results of the laboratory of ecological physiology and product quality of the Institute of Animal Biology of NAAS for twenty years of its activity. The results of basic research and applied developments obtained during the implementation of tasks included in the scientific programs of NAAS and the Scientific and Methodological Center “Animal Physiology” are presented. The main characteristics of the physiological impact of new effective feed additives and BAS, tested in production and implemented on different species of animals — cattle, sheep, poultry, rabbits, bees, in pond fish, substantiated methods of their use. The relationship between the degree of man-made pollution and the intensity of physiological and biochemical processes in animals, their adaptive and reproductive capacity. The method of arterio-venous difference in the mammary gland revealed some mechanisms of physiological influence of Cd in the body of cows during lactation under conditions of experimental loading of its salts of different concentrations, the level of biotransformation into milk. The study of the biological action of new organic compounds Se in cows, calves and breeding bulls was started for the first time. The composition of the feed additive based on the drug “Sel-Pleks” was developed and tested, which increases the immunobiological, productive and reproductive ability of the body of cows in the conditions of intensive technogenic load. New scientific data on the biological action of the developed protein-mineral supplements in the body of rabbits with different methods of maintenance and feeding. Physiological and biochemical mechanisms of influence of terms of weaning of young rabbits on immunobiological reactivity of an organism are found out. A recipe for granular feed with high protein content has been developed and its effect on growth intensity and physiological and biochemical processes in rabbits has been studied. Possibilities of application of genetically modified feeds in animal feeding and their influence on physiological status, ecological safety and quality of production are substantiated. The influence of GMO soybeans and products of their processing on the formation of adaptive reactions and functioning of individual organs and systems in animals has been studied. The absence of a pronounced negative effect of transgenic soy on the growth and development of the organism and its reproductive ability in female animals has been proved. The effect of Ge in the form of germanium citrate, obtained by nanotechnological method and chemically synthesized, on the state of the immune, reproductive antioxidant and detoxification systems of the body in laboratory rats of two generations has been studied. The peculiarities of ontogenetic development of male F₁ rats under the action of different doses of germanium citrate have been elucidated. The possibility of using small and medium doses of germanium citrate to stimulate the body’s immune and antioxidant systems, its reproductive capacity in females of multiple animals is substantiated. Changes in physiological and biochemical parameters of blood and detoxification ability of rats F₀ and F₁ under the action of different doses of germanium citrate were established. The effect of different doses of germanium citrate on the content of biotic mineral elements in tissues and organs of animals has been studied. Peculiarities of histological structure of tissues of immunocompetent organs of female F₁ rats under the action of different doses of germanium citrate are noted. The role of the laboratory staff in the improvement of existing and development of new methods of physiological, biochemical and ecological research, State standards, the possibility of their adaptation and harmonization to modern conditions of science and production is shown.

Key words: laboratory achievements, research methods, development, cattle, sheep, poultry, rabbits, bees, fish

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