ULTRASTRUCTURAL CHARACTERISTIC OF RATS LIVER OF THE THIRD GENERATION WITH THE INFLUENCE OF GENETICALLY MODIFIED AND TRADITIONAL SOYBEAN
I. M. Samsonuyk, G. I. Kotcumbas
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Lviv National University of Veterinary Medicine and Biotechnologies named after S. Z. Gzhytskyj, Pekarska st., 50, Lviv, 79010, Ukraine
Summary the article discusses the results of electronic microscopic researches of the rats’ liver of the third generation which were fed with the genetically modified and traditional soybean.
Object of the research were 42 rats of the Wistar line, weight of 160–180 g, age of 3.5–4 months. Three groups were formed, 14 rats in each group. The first group was the control, the second group-forage with the 20 % of traditional soya bean and the third group — forage with the 20 % of gm soybean. Three generation were obtained.
Histologically, the liver of rats of the first generations that were fed genetically modified soy found contravention lamellar structure and granular degeneration of hepatocytes. In the second and third generations against the backdrop of the stored patterns observed hepatocyte enlargement perysynusoyidalnyh spaces, blood supply vessels and expansion of the bile ducts. For in-depth study conducted electron microscopic examination of the liver
Ultrastructurally were discovered in the rats liver, fed with gm soybean, the nucleus with the reduced content of chromatin, the rise of peroxisome medium swelling of mitochondrion and the lowering of crystae level and expressed broadening of bilious capillary among cells. All that submicroscopic changes point on the energetic load and activation of disintoxicant processes of these cells that probably are caused by continuous toxic influence of certain elements that were received with the forage.
Keywords: RATS, GMO, LIVER, HEPATOCYT, CYTOPLASM, MITOCHONDRIA, NUCLEUS, PEROXISOMES, BILE CAPILLARIES
