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Bìol. Tvarin, 2013, volume 15, issue 1, pp. 101–107

STATE OF SYSTEM OF ANTIOXIDANT DEFENCE AND PRODUCTIVITY OF PIGLETS FOR ACTIONS OF VITAMINS A, D3, Е, L-ARGININE AND ZINC IN FORM LIPOSOMAL EMULSION

N. Z. Ohorodnyk, O.I.Vischur, I. V.Kychun

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Institute of Animal Biology NAAS,
38 V. Stus St, Lviv, 79034, Ukraine

Weaning piglets fromsows is a powerful stress factor that increases lipid peroxidation, decreases immune potential and antioxidant defence of piglets. In order to normalize processes of lipid peroxidation and to increase the system of antioxidant defence of animal natural antioxidants are used in veterinary medicinevitamins, minerals, amino acids. However, their used as conventional forms has a significant drawback they are rapidly metabolized and excreted from an organism.

The aim of the work was to determine the influence of vitamins A, D3, E, L-arginine and zinc in the form of liposomal emulsion on activity of enzymes of antioxidant system, content of products of lipid peroxidation and the productivity of piglets after weaning from sows. The experiments was conducted on piglets of large white breed, which 2 days before weaning parenterally injected of investigated components in form liposomal emulsion, by a dose 0,1 ml/kg of body weight. It is set that introduction of vitamins A, D3, E, l-arginine and zinc in the blood of piglets on the 10th day after weaning decreased content of lipid hydroperoxides and TBA-active products. Thus in plasma of blood on 5th days after weaning increased the activity of glutathione peroxidase, and in the erythrocytes activity of superoxide dismutase and catalase and increased the content of reduced glutathione. Average daily body weightgrowth increases in piglets of experimental group for the actions of the probed factors were on 16,6 % more than in pigletsof the control group. The data obtained suggest efficiency of application of vitamins A, D3, E, l-arginine and zinc in form liposomal emulsion with in order of normalization of the system of antioxidant defence and increase of the productivity of piglets.

Keywords: PIGLETS, BLOOD, WEANING, LIPOSOMAL PREPARATION, FAT-SOLUBLE VITAMINS A, D3, E, L-ARGININE, ZINC, ANTIOXIDANT SYSTEM, LIPID PEROXIDATION PRODUCTS, PRODUCTIVITY

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